RSF1

RSF1
Identifiers
Aliases	RSF1, HBXAP, RSF-1, XAP8, p325, remodeling and spacing factor 1
External IDs	OMIM: 608522; MGI: 2682305; HomoloGene: 41142; GeneCards: RSF1; OMA:RSF1 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	77,820,869 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	97,341,985 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; internal globus pallidus; ; sural nerve; ; epithelium of colon; ; tendon of biceps brachii; ; cerebellar vermis; ; Brodmann area 23; ; pars reticulata; ; middle temporal gyrus; ; external globus pallidus;
	Top expressed in
	hand; ; Rostral migratory stream; ; tail of embryo; ; genital tubercle; ; ventromedial nucleus; ; lateral septal nucleus; ; otolith organ; ; olfactory tubercle; ; utricle; ; maxillary prominence;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	histone binding; ATPase activity; protein binding; metal ion binding; histone acetyltransferase activity;
Cellular component	RSF complex; nucleus; nucleoplasm; histone acetyltransferase complex;
Biological process	positive regulation of transcription, DNA-templated; negative regulation of DNA binding; chromatin remodeling; positive regulation of viral transcription; negative regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; CENP-A containing chromatin assembly; transcription, DNA-templated; DNA-templated transcription, initiation; nucleosome assembly; chromatin organization; histone acetylation; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	51773
	233532
	ENSG00000048649
	ENSMUSG00000035623
	Q96T23; Q05DG0
	n/a
	NM_016578
	NM_001081267
	NP_057662; NP_057662.3
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Remodeling and spacing factor 1 is a protein that in humans is encoded by the RSF1 gene.

HBXAP is involved in transcription repression, transcription coactivation when associated with hepatitis B virus X protein (HBX), and chromatin remodeling and spacing when associated with SNF2H (MIM 603375).[supplied by OMIM]