RUVBL2

RUVBL2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2CQA, 2XSZ, 3UK6
Identifiers
Aliases	RUVBL2, ECP51, INO80J, REPTIN, RVB2, TIH2, TIP48, TIP49B, CGI-46, ECP-51, TAP54-beta, RuvB like AAA ATPase 2
External IDs	OMIM: 604788; MGI: 1342299; HomoloGene: 4856; GeneCards: RUVBL2; OMA:RUVBL2 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	49,015,970 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	45,087,520 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; bronchial epithelial cell; ; right uterine tube; ; olfactory zone of nasal mucosa; ; mucosa of paranasal sinus; ; ventricular zone; ; parotid gland; ; tendon of biceps brachii; ; embryo;
	Top expressed in
	epiblast; ; somite; ; tail of embryo; ; embryo; ; mandibular prominence; ; embryo; ; primitive streak; ; maxillary prominence; ; morula; ; ventricular zone;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding; nucleotide binding; 5'-3' DNA helicase activity; helicase activity; unfolded protein binding; DNA helicase activity; ATPase activity; protein binding; identical protein binding; chromatin DNA binding; ATP binding; hydrolase activity; RNA polymerase II core promoter sequence-specific DNA binding; TFIID-class transcription factor complex binding; protein homodimerization activity; ADP binding; ATPase binding;
Cellular component	membrane; nuclear matrix; NuA4 histone acetyltransferase complex; intracellular anatomical structure; nucleoplasm; MLL1 complex; extracellular exosome; nucleus; Swr1 complex; R2TP complex; cytoplasm; centrosome; cytosol; Ino80 complex;
Biological process	chromatin remodeling; DNA recombination; regulation of transcription, DNA-templated; cellular response to UV; histone H2A acetylation; cellular response to estradiol stimulus; transcription, DNA-templated; positive regulation of histone acetylation; cellular response to DNA damage stimulus; establishment of protein localization to chromatin; protein folding; positive regulation of telomerase RNA localization to Cajal body; histone H4 acetylation; regulation of growth; DNA repair; positive regulation of transcription by RNA polymerase II; DNA duplex unwinding; box C/D snoRNP assembly;
	Sources:Amigo / QuickGO
Orthologs
	10856
	20174
	ENSG00000183207
	ENSMUSG00000003868
	Q9Y230
	Q9WTM5
	NM_006666; NM_001321190; NM_001321191
	NM_011304
	NP_001308119; NP_001308120; NP_006657
	NP_035434
	Wikidata
View/Edit Human	View/Edit Mouse

RuvB-like 2 (E. coli), also known as RUVBL2, is a human gene coding for a protein belonging to the AAA+ family of proteins.