Ralmitaront

Ralmitaront
Clinical data
Other names	RG-7906; RG7906; RO-6889450; RO6889450
Identifiers
	IUPAC name 5-Ethyl-4-methyl-N-[4-[(2S)-morpholin-2-yl]phenyl]-1H-pyrazole-3-carboxamide;
CAS Number	2133417-13-5;
PubChem CID	130429734;
ChemSpider	88298290;
UNII	QA8MW1Q80P;
KEGG	D11830;
ChEMBL	ChEMBL4594376;
CompTox Dashboard (EPA)	DTXSID901336976 ;
Chemical and physical data
Formula	C17H22N4O2
Molar mass	314.389 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC1=C(C(=NN1)C(=O)NC2=CC=C(C=C2)[C@H]3CNCCO3)C;
	InChI InChI=1S/C17H22N4O2/c1-3-14-11(2)16(21-20-14)17(22)19-13-6-4-12(5-7-13)15-10-18-8-9-23-15/h4-7,15,18H,3,8-10H2,1-2H3,(H,19,22)(H,20,21)/t15-/m1/s1; Key:XHHXGKRFUPEPFM-OAHLLOKOSA-N;

Ralmitaront (INNTooltip International Nonproprietary Name, USANTooltip United States Adopted Name; developmental code names RG-7906 and RO-6889450) is an investigational antipsychotic drug which was undergoing a Phase II clinical trial for the treatment of negative symptoms in schizophrenia and schizoaffective disorder, but the trial was discontinued due to lack of efficacy. Another Phase II clinical trial targeting acute psychotic symptoms of schizophrenia was also terminated for the same reason. It is a partial agonist of the TAAR1 protein. The medication is being developed by the pharmaceutical company Hoffmann-La Roche. Ralmitaront had completed Phase I clinical trials.