Receptor activity-modifying protein
| Receptor activity-modifying protein | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | RAMP | ||||||||
| Pfam | PF04901 | ||||||||
| InterPro | IPR006985 | ||||||||
| Membranome | 10 | ||||||||
| |||||||||
| Receptor activity-modifying protein 1 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | RAMP1 | ||||||
| NCBI gene | 10267 | ||||||
| HGNC | 9843 | ||||||
| OMIM | 605153 | ||||||
| RefSeq | NM_005855 | ||||||
| UniProt | O60894 | ||||||
| Other data | |||||||
| Locus | Chr. 2 q36-37.1 | ||||||
| |||||||
| Receptor activity-modifying protein 2 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | RAMP2 | ||||||
| NCBI gene | 10266 | ||||||
| HGNC | 9844 | ||||||
| OMIM | 605154 | ||||||
| RefSeq | NM_005854 | ||||||
| UniProt | O60895 | ||||||
| Other data | |||||||
| Locus | Chr. 17 q12-21.1 | ||||||
| |||||||
| Receptor activity-modifying protein 3 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | RAMP3 | ||||||
| NCBI gene | 10268 | ||||||
| HGNC | 9845 | ||||||
| OMIM | 605155 | ||||||
| RefSeq | NM_005856 | ||||||
| UniProt | O60896 | ||||||
| Other data | |||||||
| Locus | Chr. 7 q13-p12 | ||||||
| |||||||
Receptor activity-modifying proteins (RAMPs) are a class of protein that interact with and modulate the activities of several Class B G protein-coupled receptors including the receptors for secretin, calcitonin (CT), glucagon, and vasoactive intestinal peptide (VIP). There are three distinct types of RAMPs in mammals (though more in fish), designated RAMP1, RAMP2, and RAMP3, each encoded by a separate gene.