Distal renal tubular acidosis

Distal renal tubular acidosis
Other namesType 1 renal tubular acidosis
Radiograph of a person with rickets, a complication of both distal and proximal RTA.

Distal renal tubular acidosis (dRTA) is the classical form of RTA, being the first described. Distal RTA is characterized by a failure of acid secretion by the alpha intercalated cells of the distal tubule and cortical collecting duct of the distal nephron. This failure of acid secretion may be due to a number of causes. It leads to relatively alkaline urine, due to the kidney's inability to acidify the urine to a pH of less than 5.3.

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