Replication terminator protein
| Replication terminator protein | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | RTP | ||||||||
| Pfam | PF02334 | ||||||||
| InterPro | IPR003432 | ||||||||
| SCOP2 | 1bm9 / SCOPe / SUPFAM | ||||||||
| |||||||||
The replication terminator protein (RTP) is a DNA-binding protein that helps terminate DNA replication in Bacillus. It has a winged-helix structure and forms a homodimer via hydrogen bonds. The dimer is symmetric when it is not bound to DNA, but becomes asymmetrical when it is bound. Its termination activity is polar: it stops the replication fork from continuing in one direction, but a fork going the other direction is allowed to proceed.