Retifanlimab

Retifanlimab
Monoclonal antibody
TypeWhole antibody
SourceHumanized
TargetProgrammed cell death protein 1 (PD-1)
Clinical data
Trade namesZynyz
Other namesAEX-1188, INCMGA-00012, MGA-012, retifanlimab-dlwr
AHFS/Drugs.comZynyz
MedlinePlusa623017
License data
Routes of
administration
Intravenous
ATC code
Legal status
Legal status
Identifiers
CAS Number
DrugBank
UNII
KEGG
Chemical and physical data
FormulaC6456H9934N1702O2032S46
Molar mass145381.13 g·mol−1

Retifanlimab, sold under the brand name Zynyz, is an anti-cancer medication used for the treatment of Merkel cell carcinoma. Retifanlimab is a programmed death receptor-1 (PD-1)–blocking monoclonal antibody.

It was approved for medical use in the United States in March 2023, and in the European Union in April 2024.