Ribosome recycling factor

MRRF
Identifiers
Aliases	MRRF, MRFF, MTRRF, RRF, mitochondrial ribosome recycling factor
External IDs	OMIM: 604602; MGI: 1915121; HomoloGene: 12203; GeneCards: MRRF; OMA:MRRF - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	122,331,337 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	36,080,659 bp
RNA expression pattern
	Top expressed in
	rectum; ; left testis; ; right testis; ; mucosa of transverse colon; ; right uterine tube; ; gastrocnemius muscle; ; right lobe of liver; ; left lobe of thyroid gland; ; right lobe of thyroid gland; ; apex of heart;
	Top expressed in
	tail of embryo; ; genital tubercle; ; interventricular septum; ; endothelial cell of lymphatic vessel; ; Paneth cell; ; spermatid; ; external carotid artery; ; condyle; ; muscle of thigh; ; left lobe of liver;
	More reference expression data
	n/a
Gene ontology
Molecular function	ribosomal large subunit binding;
Cellular component	mitochondrial matrix; mitochondrion;
Biological process	ribosome disassembly; protein biosynthesis; mitochondrial translational termination;
	Sources:Amigo / QuickGO
Orthologs
	92399
	67871
	ENSG00000148187
	ENSMUSG00000026887
	Q96E11
	Q9D6S7
NM_001173512; NM_138777; NM_199176; NM_199177; NM_001346339;
	NM_001346341; NM_001346343; NM_001346345; NM_001346347
	NM_026422
NP_001166983; NP_001333268; NP_001333270; NP_001333272; NP_001333274;
	NP_001333276; NP_620132; NP_954646
	NP_080698
	Wikidata
View/Edit Human	View/Edit Mouse

Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Ribosome recycling factor
Ribosome recycling factor
Identifiers
Symbol	RRF
Pfam	PF01765
InterPro	IPR002661
CATH	1ek8
SCOP2	1ek8 / SCOPe / SUPFAM
CDD	cd00520
Pfam
Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Ribosome recycling factor or ribosome release factor (RRF) is a protein found in bacterial cells as well as eukaryotic organelles, specifically mitochondria and chloroplasts. It functions to recycle ribosomes after completion of protein synthesis (bacterial translation). In humans, the mitochrondrial version is coded by the MRRF gene.