Risedronic acid

Risedronic acid
Clinical data
Trade namesActonel, Atelvia, Benet, others
AHFS/Drugs.comMonograph
License data
Pregnancy
category
  • AU: B3
Routes of
administration
By mouth
ATC code
Legal status
Legal status
  • AU: S4 (Prescription only)
  • UK: POM (Prescription only)
  • US: ℞-only
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability0.63%
Protein binding~24%
MetabolismNone
Elimination half-life1.5 h
ExcretionKidney and fecal
Identifiers
  • (1-hydroxy-1-phosphono-2-pyridin-3-yl-ethyl)phosphonic acid
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
PDB ligand
CompTox Dashboard (EPA)
ECHA InfoCard100.116.436
Chemical and physical data
FormulaC7H11NO7P2
Molar mass283.113 g·mol−1
3D model (JSmol)
  • OC(Cc1cccnc1)(P(=O)(O)O)P(=O)(O)O
  • InChI=1S/C7H11NO7P2/c9-7(16(10,11)12,17(13,14)15)4-6-2-1-3-8-5-6/h1-3,5,9H,4H2,(H2,10,11,12)(H2,13,14,15) N
  • Key:IIDJRNMFWXDHID-UHFFFAOYSA-N N
 NY (what is this?)  (verify)

Risedronic acid, often used as its sodium salt risedronate sodium, is a bisphosphonate. It slows down the cells which break down bone. It's used to treat or prevent osteoporosis, and treat Paget's disease of bone. It is taken by mouth.

It was patented in 1984 and approved for medical use in 1998.