S100B

S100B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1MQ1, 1UWO, 2H61, 2M49, 2PRU, 3CZT, 3D0Y, 3D10, 3HCM, 4XYN, 5CSJ, 5CSF, 5CSN, 5CSI
Identifiers
Aliases	S100B, NEF, S100, S100-B, S100beta, S100 calcium binding protein B
External IDs	OMIM: 176990; MGI: 98217; HomoloGene: 4567; GeneCards: S100B; OMA:S100B - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	46,605,208 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	76,096,993 bp
RNA expression pattern
	Top expressed in
	C1 segment; ; inferior ganglion of vagus nerve; ; olfactory bulb; ; subthalamic nucleus; ; trigeminal ganglion; ; internal globus pallidus; ; Medulla Oblongata; ; superior vestibular nucleus; ; substantia nigra; ; pars reticulata;
	Top expressed in
	vestibular membrane of cochlear duct; ; lobe of cerebellum; ; anterior horn of spinal cord; ; cerebellar vermis; ; deep cerebellar nuclei; ; stria vascularis; ; pontine nuclei; ; facial motor nucleus; ; optic nerve; ; utricle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; S100 protein binding; protein homodimerization activity; zinc ion binding; metal ion binding; calcium-dependent protein binding; protein binding; identical protein binding; tau protein binding; signaling receptor binding; RAGE receptor binding;
Cellular component	cytoplasm; ruffle; extracellular region; soma; perinuclear region of cytoplasm; nucleus; extracellular space;
Biological process	axonogenesis; response to glucocorticoid; memory; negative regulation of skeletal muscle cell differentiation; central nervous system development; astrocyte differentiation; positive regulation of synaptic transmission; positive regulation of cell population proliferation; regulation of cell shape; positive regulation of apoptotic process; learning or memory; positive regulation of I-kappaB kinase/NF-kappaB signaling; regulation of neuronal synaptic plasticity; response to methylmercury; cell population proliferation; innate immune response; cellular response to hypoxia; long-term potentiation; positive regulation of myelination;
	Sources:Amigo / QuickGO
Orthologs
	6285
	20203
	ENSG00000160307
	ENSMUSG00000033208
	P04271
	P50114
	NM_006272
	NM_009115
	NP_006263
	NP_033141
	Wikidata
View/Edit Human	View/Edit Mouse

S100 calcium-binding protein B (S100B) is a protein of the S100 protein family.

S100 proteins are localized in the cytoplasm and nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3.