SAE1

SAE1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1Y8Q, 1Y8R, 3KYC, 3KYD
Identifiers
Aliases	SAE1, AOS1, HSPC140, SUA1, UBLE1A, SUMO1 activating enzyme subunit 1
External IDs	OMIM: 613294; MGI: 1929264; HomoloGene: 4019; GeneCards: SAE1; OMA:SAE1 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	47,210,636 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	16,121,731 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; muscle layer of sigmoid colon; ; stromal cell of endometrium; ; left testis; ; right testis; ; gonad; ; oocyte; ; prefrontal cortex; ; smooth muscle tissue;
	Top expressed in
	ventricular zone; ; epiblast; ; primitive streak; ; somite; ; abdominal wall; ; mandibular prominence; ; neural tube; ; maxillary prominence; ; yolk sac; ; tail of embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ubiquitin activating enzyme activity; SUMO activating enzyme activity; enzyme activator activity; ligase activity; protein C-terminus binding; ubiquitin-like modifier activating enzyme activity; protein binding; ATP-dependent protein binding; small protein activating enzyme binding; protein heterodimerization activity;
Cellular component	SUMO activating enzyme complex; nucleus; nucleoplasm; cytoplasm;
Biological process	protein sumoylation; protein ubiquitination; positive regulation of protein targeting to mitochondrion; positive regulation of catalytic activity;
	Sources:Amigo / QuickGO
Orthologs
	10055
	56459
	ENSG00000142230
	ENSMUSG00000052833
	Q9UBE0
	Q9R1T2
	NM_001145713; NM_001145714; NM_005500
	NM_001285891; NM_001285892; NM_019748
	NP_001139185; NP_001139186; NP_005491
	NP_001272820; NP_001272821; NP_062722
	Wikidata
View/Edit Human	View/Edit Mouse

SUMO-activating enzyme subunit 1 is a protein that in humans is encoded by the SAE1 gene.