SASH1

SASH1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2EBP
Identifiers
Aliases	SASH1, SH3D6A, dJ323M4, dJ323M4.1, SAM and SH3 domain containing 1, DUH1, CAPOK
External IDs	OMIM: 607955; MGI: 1917347; HomoloGene: 69182; GeneCards: SASH1; OMA:SASH1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	148,552,044 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	8,761,814 bp
RNA expression pattern
	Top expressed in
	synovial joint; ; external globus pallidus; ; skin of hip; ; subthalamic nucleus; ; skin of thigh; ; inferior ganglion of vagus nerve; ; oral cavity; ; pars reticulata; ; Achilles tendon; ; lateral nuclear group of thalamus;
	Top expressed in
	stroma of bone marrow; ; transitional epithelium of urinary bladder; ; medial geniculate nucleus; ; lateral geniculate nucleus; ; substantia nigra; ; suprachiasmatic nucleus; ; ventral tegmental area; ; medial dorsal nucleus; ; lateral hypothalamus; ; deep cerebellar nuclei;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	mitogen-activated protein kinase kinase kinase binding; molecular adaptor activity; protein C-terminus binding; protein kinase binding;
Cellular component	protein-containing complex;
Biological process	positive regulation of endothelial cell migration; positive regulation of lipopolysaccharide-mediated signaling pathway; positive regulation of JUN kinase activity; regulation of protein K63-linked ubiquitination; positive regulation of p38MAPK cascade; regulation of protein autoubiquitination; protein polyubiquitination; positive regulation of NIK/NF-kappaB signaling; positive regulation of angiogenesis;
	Sources:Amigo / QuickGO
Orthologs
	23328
	70097
	ENSG00000111961
	ENSMUSG00000015305
	O94885
	P59808
NM_015278; NM_001346505; NM_001346506; NM_001346507; NM_001346508;
	NM_001346509
	NM_175155
NP_001333434; NP_001333435; NP_001333436; NP_001333437; NP_001333438;
	NP_056093
	NP_780364
	Wikidata
View/Edit Human	View/Edit Mouse

SAM and SH3 domain-containing protein 1 is a protein that in humans is encoded by the SASH1 gene.