SAT2

SAT2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2BEI, 2Q4V
Identifiers
Aliases	SAT2, Sspermidine/spermine N1-acetyltransferase family member 2, SSAT-2
External IDs	OMIM: 611463; MGI: 1916465; HomoloGene: 44215; GeneCards: SAT2; OMA:SAT2 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	7,627,876 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	69,514,696 bp
RNA expression pattern
	Top expressed in
	right adrenal cortex; ; left adrenal cortex; ; jejunal mucosa; ; right lobe of liver; ; mucosa of ileum; ; duodenum; ; human kidney; ; left ovary; ; right ovary; ; anterior pituitary;
	Top expressed in
	otolith organ; ; utricle; ; retinal pigment epithelium; ; right kidney; ; proximal tubule; ; otic vesicle; ; Rostral migratory stream; ; internal carotid artery; ; external carotid artery; ; epithelium of lens;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; N-acetyltransferase activity; acyltransferase activity; diamine N-acetyltransferase activity; protein binding; identical protein binding; spermidine binding;
Cellular component	cytoplasm; extracellular exosome;
Biological process	putrescine acetylation; spermine acetylation; nor-spermidine metabolic process; spermidine acetylation; putrescine catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	112483
	69215
	ENSG00000141504
	ENSMUSG00000069835
	Q96F10
	Q6P8J2
	NM_133491; NM_001320845; NM_001320846; NM_001320847
	NM_026991; NM_001356468; NM_001356469
	NP_001307774; NP_001307775; NP_001307776; NP_597998
	NP_081267; NP_001343397; NP_001343398
	Wikidata
View/Edit Human	View/Edit Mouse

Diamine acetyltransferase 2 is an enzyme that in humans is encoded by the SAT2 gene. SAT2 maintains a key metabolic glutamine/glutamate balance underpinning retrograde signaling by dendritic release of the neurotransmitter glutamate.