SCG2

SCG2
Identifiers
Aliases	SCG2, CHGC, SN, SgII, secretogranin II
External IDs	OMIM: 118930; MGI: 103033; HomoloGene: 2591; GeneCards: SCG2; OMA:SCG2 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	223,602,361 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	79,417,837 bp
RNA expression pattern
	Top expressed in
	beta cell; ; lateral nuclear group of thalamus; ; superior vestibular nucleus; ; pituitary gland; ; Hypothalamus; ; nucleus accumbens; ; pars compacta; ; middle temporal gyrus; ; anterior pituitary; ; pars reticulata;
	Top expressed in
	islet of Langerhans; ; dorsomedial hypothalamic nucleus; ; ventral tegmental area; ; arcuate nucleus; ; ventromedial nucleus; ; mammillary body; ; paraventricular nucleus of hypothalamus; ; dorsal tegmental nucleus; ; median eminence; ; adrenal gland;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; chemoattractant activity; cytokine activity;
Cellular component	extracellular region; dense core granule; secretory granule; extracellular space; neuronal dense core vesicle; endoplasmic reticulum lumen;
Biological process	protein secretion; induction of positive chemotaxis; negative regulation of endothelial cell apoptotic process; eosinophil chemotaxis; positive chemotaxis; negative regulation of extrinsic apoptotic signaling pathway; intracellular signal transduction; inflammatory response; positive regulation of endothelial cell proliferation; endothelial cell migration; angiogenesis; MAPK cascade; negative regulation of endothelial cell proliferation; post-translational protein modification; regulation of signaling receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	7857
	20254
	ENSG00000171951
	ENSMUSG00000050711
	P13521; P15321
	Q03517
	NM_003469
	NM_009129; NM_001310680
	NP_003460
	NP_001297609; NP_033155
	Wikidata
View/Edit Human	View/Edit Mouse

SCG2, also called secretogranin II (chromogranin C), is a protein which in humans is encoded by the SCG2 gene.