SCN3B

SCN3B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4L1D
Identifiers
Aliases	SCN3B, ATFB16, BRGDA7, HSA243396, SCNB3, sodium voltage-gated channel beta subunit 3
External IDs	OMIM: 608214; MGI: 1918882; HomoloGene: 10176; GeneCards: SCN3B; OMA:SCN3B - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	123,655,244 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	40,202,914 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; orbitofrontal cortex; ; Brodmann area 46; ; entorhinal cortex; ; superior frontal gyrus; ; Region I of hippocampus proper; ; prefrontal cortex; ; postcentral gyrus; ; dorsolateral prefrontal cortex; ; Brodmann area 23;
	Top expressed in
	superior cervical ganglion; ; Region I of hippocampus proper; ; olfactory epithelium; ; dentate gyrus; ; hippocampus proper; ; external carotid artery; ; dentate gyrus of hippocampal formation granule cell; ; nucleus accumbens; ; piriform cortex; ; ventral tegmental area;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	sodium channel regulator activity; transmembrane transporter binding; sodium channel activity; voltage-gated ion channel activity; voltage-gated sodium channel activity involved in cardiac muscle cell action potential; voltage-gated sodium channel activity; sodium channel inhibitor activity;
Cellular component	voltage-gated sodium channel complex; integral component of membrane; membrane; plasma membrane; Z discdkac;
Biological process	regulation of ventricular cardiac muscle cell membrane depolarization; membrane depolarization during action potential; cardiac muscle contraction; sodium ion transmembrane transport; sodium ion transport; SA node cell action potential; regulation of atrial cardiac muscle cell membrane depolarization; membrane depolarization; ventricular cardiac muscle cell action potential; regulation of ion transmembrane transport; cardiac muscle cell action potential involved in contraction; ion transport; nervous system development; positive regulation of heart rate; cardiac conduction; regulation of sodium ion transmembrane transporter activity; atrial cardiac muscle cell action potential; positive regulation of sodium ion transport; sensory perception of pain; protein localization to plasma membrane; regulation of heart rate by cardiac conduction; membrane depolarization during cardiac muscle cell action potential;
	Sources:Amigo / QuickGO
Orthologs
	55800
	235281
	ENSG00000166257
	ENSMUSG00000049281
	Q9NY72
	Q8BHK2
	NM_001040151; NM_018400
	NM_001083917; NM_001286614; NM_153522; NM_178227; NM_001359700
	NP_001035241; NP_060870
	NP_001077386; NP_001273543; NP_839941; NP_001346629
	Wikidata
View/Edit Human	View/Edit Mouse

Sodium channel subunit beta-3 is a protein that in humans is encoded by the SCN3B gene. Two alternatively spliced variants, encoding the same protein, have been identified.