SCN7A

SCN7A
Identifiers
Aliases	SCN7A, NaG, Nav2.1, Nav2.2, SCN6A, sodium voltage-gated channel alpha subunit 7
External IDs	OMIM: 182392; MGI: 102965; HomoloGene: 55706; GeneCards: SCN7A; OMA:SCN7A - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	166,611,482 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	66,615,258 bp
RNA expression pattern
	Top expressed in
	trigeminal ganglion; ; sural nerve; ; right lung; ; spinal ganglia; ; lower lobe of lung; ; seminal vesicula; ; right ventricle; ; left ovary; ; visceral pleura; ; muscle layer of sigmoid colon;
	Top expressed in
	left lung lobe; ; carotid body; ; median eminence; ; lumbar spinal ganglion; ; right lung; ; right lung lobe; ; white adipose tissue; ; trigeminal ganglion; ; arcuate nucleus; ; aortic valve;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ion channel activity; sodium channel activity; voltage-gated ion channel activity; voltage-gated sodium channel activity;
Cellular component	voltage-gated sodium channel complex; integral component of membrane; plasma membrane; membrane; axon; glial cell projection;
Biological process	regulation of ion transmembrane transport; muscle contraction; membrane depolarization during action potential; ion transport; sodium ion transmembrane transport; transmembrane transport; neuronal action potential; sodium ion transport; ion transmembrane transport; response to bacterium; sodium ion homeostasis;
	Sources:Amigo / QuickGO
Orthologs
	6332
	20272
	ENSG00000136546
	ENSMUSG00000034810
	Q01118
	n/a
	NM_002976
	NM_009135
	NP_002967
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Na_x is a protein that in humans is encoded by the SCN7A (Sodium channel protein type 7) gene. It is a sodium channel alpha subunit expressed in the heart, the uterus and in glial cells of mice. It has low similarity to all nine other sodium channel alpha subunits (Na_v1.1–1.9).