Syntenin-1

SDCBP
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1N99, 1NTE, 1OBX, 1OBY, 1OBZ, 1R6J, 1V1T, 1W9E, 1W9O, 1W9Q, 1YBO, 4Z33
Identifiers
Aliases	SDCBP, MDA-9, ST1, SYCL, TACIP18, MDA9, syndecan binding protein
External IDs	OMIM: 602217; MGI: 1337026; HomoloGene: 4110; GeneCards: SDCBP; OMA:SDCBP - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	58,582,859 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	6,408,423 bp
RNA expression pattern
	Top expressed in
	retinal pigment epithelium; ; visceral pleura; ; amniotic fluid; ; palpebral conjunctiva; ; parietal pleura; ; germinal epithelium; ; blood; ; skin of hip; ; ganglionic eminence; ; monocyte;
	Top expressed in
	stroma of bone marrow; ; gastrula; ; fetal liver hematopoietic progenitor cell; ; pyloric antrum; ; calvaria; ; tibiofemoral joint; ; atrioventricular valve; ; right lung; ; mucous cell of stomach; ; submandibular gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein N-terminus binding; frizzled binding; protein binding; identical protein binding; cytoskeletal anchor activity; interleukin-5 receptor binding; phosphatidylinositol-4,5-bisphosphate binding; lipid binding; cadherin binding; syndecan binding; protein heterodimerization activity;
Cellular component	cytoplasm; extracellular vesicle; blood microparticle; endoplasmic reticulum membrane; membrane; focal adhesion; melanosome; adherens junction; plasma membrane; cell junction; endoplasmic reticulum; membrane raft; extracellular exosome; cytoskeleton; nucleus; extracellular region; extracellular space; nucleoplasm; cytosol; interleukin-5 receptor; nuclear membrane; azurophil granule lumen; intracellular membrane-bounded organelle;
Biological process	positive regulation of transforming growth factor beta receptor signaling pathway; intracellular signal transduction; positive regulation of extracellular exosome assembly; negative regulation of receptor internalization; protein targeting to membrane; ephrin receptor signaling pathway; substrate-dependent cell migration, cell extension; positive regulation of pathway-restricted SMAD protein phosphorylation; positive regulation of JNK cascade; positive regulation of epithelial to mesenchymal transition; regulation of mitotic cell cycle; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of exosomal secretion; positive regulation of phosphorylation; actin cytoskeleton organization; chemical synaptic transmission; positive regulation of cell population proliferation; positive regulation of cell growth; positive regulation of cell migration; neutrophil degranulation;
	Sources:Amigo / QuickGO
Orthologs
	6386
	53378
	ENSG00000137575
	ENSMUSG00000028249
	O00560
	O08992
NM_001007067; NM_001007068; NM_001007069; NM_001007070; NM_005625;
	NM_001330537; NM_001348339; NM_001348340; NM_001348341
	NM_001098227; NM_016807
NP_001007068; NP_001007069; NP_001007070; NP_001007071; NP_001317466;
	NP_005616; NP_001335268; NP_001335269; NP_001335270
	NP_001091697; NP_058087
	Wikidata
View/Edit Human	View/Edit Mouse

Syntenin-1 is a protein that in humans is encoded by the SDCBP gene.