SEC13

SEC13
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3BG0, 3BG1, 5A9Q
Identifiers
Aliases	SEC13, D3S1231E, SEC13L1, SEC13R, npp-20, SEC13 homolog, nuclear pore and COPII coat complex component
External IDs	OMIM: 600152; MGI: 99832; HomoloGene: 6479; GeneCards: SEC13; OMA:SEC13 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	10,321,112 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	113,717,704 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; oocyte; ; pituitary gland; ; beta cell; ; anterior pituitary; ; duodenum; ; jejunal mucosa; ; parotid gland; ; cartilage tissue; ; tibia;
	Top expressed in
	molar; ; epithelium of small intestine; ; seminal vesicula; ; otic placode; ; Ileal epithelium; ; mandibular prominence; ; maxillary prominence; ; endocardial cushion; ; neural tube; ; duodenum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; identical protein binding; structural molecule activity;
Cellular component	endoplasmic reticulum membrane; intracellular membrane-bounded organelle; membrane; nuclear envelope; nuclear pore; nucleoplasm; GATOR2 complex; nuclear pore outer ring; endoplasmic reticulum; ER to Golgi transport vesicle membrane; extracellular exosome; cytoplasmic vesicle; nucleus; kinetochore; Golgi membrane; lysosome; lysosomal membrane; COPII vesicle coat; cytosol; host cell;
Biological process	mRNA transport; antigen processing and presentation of exogenous peptide antigen via MHC class II; antigen processing and presentation of peptide antigen via MHC class I; COPII vesicle coating; protein transport; intracellular protein transport; vesicle-mediated transport; positive regulation of TOR signaling; sister chromatid cohesion; COPII-coated vesicle cargo loading; transport; protein exit from endoplasmic reticulum; COPII-coated vesicle budding; positive regulation of TORC1 signaling; regulation of glycolytic process; mRNA export from nucleus; tRNA export from nucleus; viral process; viral transcription; regulation of gene silencing by miRNA; intracellular transport of virus; regulation of cellular response to heat;
	Sources:Amigo / QuickGO
Orthologs
	6396
	110379
	ENSG00000157020
	ENSMUSG00000030298
	P55735
	Q9D1M0
	NM_001136026; NM_001136232; NM_001278946; NM_030673; NM_183352
	NM_024206
	NP_001129498; NP_001129704; NP_001265875; NP_109598; NP_899195
	NP_077168
	Wikidata
View/Edit Human	View/Edit Mouse

Protein SEC13 homolog is a protein that in humans is encoded by the SEC13 gene.

The protein encoded by this gene belongs to the SEC13 family of WD-repeat proteins. It has similarity to the yeast SEC13 and SEC31 proteins, which are required for vesicle biogenesis from the endoplasmic reticulum during the transport of proteins.