SEC24D

SEC24D
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	3EFO, 3EG9
Identifiers
Aliases	SEC24D, CLCRP2, SEC24 homolog D, COPII coat complex component
External IDs	OMIM: 607186; MGI: 1916858; HomoloGene: 40986; GeneCards: SEC24D; OMA:SEC24D - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	118,838,683 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	123,159,290 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; jejunal mucosa; ; islet of Langerhans; ; ascending aorta; ; right coronary artery; ; Descending thoracic aorta; ; right lobe of liver; ; smooth muscle tissue; ; body of pancreas; ; tibia;
	Top expressed in
	yolk sac; ; calvaria; ; ascending aorta; ; aortic valve; ; seminal vesicula; ; duodenum; ; epithelium of small intestine; ; islet of Langerhans; ; jejunum; ; umbilical cord;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; SNARE binding; zinc ion binding; metal ion binding;
Cellular component	cytoplasm; endoplasmic reticulum membrane; membrane; Golgi membrane; endoplasmic reticulum; COPII vesicle coat; cytosol; ER to Golgi transport vesicle membrane; cytoplasmic vesicle;
Biological process	antigen processing and presentation of exogenous peptide antigen via MHC class II; antigen processing and presentation of peptide antigen via MHC class I; in utero embryonic development; COPII vesicle coating; protein transport; intracellular protein transport; vesicle-mediated transport; endoplasmic reticulum to Golgi vesicle-mediated transport; COPII-coated vesicle cargo loading;
	Sources:Amigo / QuickGO
Orthologs
	9871
	69608
	ENSG00000150961
	ENSMUSG00000039234
	O94855
	n/a
	NM_014822; NM_001318066
	NM_027135
	NP_001304995; NP_055637
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Protein transport protein Sec24D is a protein that in humans is encoded by the SEC24D gene.

The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The role of this gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration.