SEL1L

SEL1L
Identifiers
Aliases	SEL1L, PRO1063, SEL1-LIKE, SEL1L1, SEL1L ERAD E3 ligase adaptor subunit, ERAD E3 ligase adaptor subunit, Hrd3, SEL1L adaptor subunit of ERAD E3 ubiquitin ligase
External IDs	OMIM: 602329; MGI: 1329016; HomoloGene: 31286; GeneCards: SEL1L; OMA:SEL1L - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	81,533,853 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	91,815,931 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; epithelium of colon; ; bone marrow cells; ; pericardium; ; decidua; ; cardia; ; pylorus; ; islet of Langerhans; ; jejunal mucosa; ; mucosa of ileum;
	Top expressed in
	submandibular gland; ; lacrimal gland; ; parotid gland; ; cumulus cell; ; Paneth cell; ; vestibular membrane of cochlear duct; ; pancreas; ; internal carotid artery; ; Rostral migratory stream; ; epithelium of stomach;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	integral component of membrane; Hrd1p ubiquitin ligase complex; endoplasmic reticulum membrane; Derlin-1 retrotranslocation complex; membrane; endoplasmic reticulum; endoplasmic reticulum quality control compartment; Hrd1p ubiquitin ligase ERAD-L complex;
Biological process	Notch signaling pathway; protein stabilization; retrograde protein transport, ER to cytosol; ubiquitin-dependent ERAD pathway; response to endoplasmic reticulum stress; endoplasmic reticulum mannose trimming; triglyceride metabolic process; protein secretion; ERAD pathway; transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	6400
	20338
	ENSG00000071537
	ENSMUSG00000020964
	Q9UBV2
	Q9Z2G6
	NM_001244984; NM_005065
	NM_001039089; NM_011344
	NP_001231913; NP_005056
	NP_001034178; NP_035474
	Wikidata
View/Edit Human	View/Edit Mouse

Protein sel-1 homolog 1 is a protein that in humans is encoded by the SEL1L gene.