SEMA4A

SEMA4A
Identifiers
Aliases	SEMA4A, CORD10, RP35, SEMAB, SEMB, semaphorin 4A
External IDs	OMIM: 607292; MGI: 107560; HomoloGene: 8425; GeneCards: SEMA4A; OMA:SEMA4A - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	156,177,752 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	88,368,489 bp
RNA expression pattern
	Top expressed in
	monocyte; ; granulocyte; ; bone marrow cells; ; blood; ; Amygdala; ; nucleus accumbens; ; skin of abdomen; ; left lobe of thyroid gland; ; retinal pigment epithelium; ; cingulate gyrus;
	Top expressed in
	granulocyte; ; Paneth cell; ; retinal pigment epithelium; ; ventromedial nucleus; ; jejunum; ; paraventricular nucleus of hypothalamus; ; arcuate nucleus; ; prostate; ; ileum; ; duodenum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; neuropilin binding; semaphorin receptor binding; chemorepellent activity;
Cellular component	integral component of membrane; nucleus; cytosol; intracellular membrane-bounded organelle; plasma membrane; extracellular space; membrane; integral component of plasma membrane;
Biological process	cell differentiation; adaptive immune response; axonogenesis; immune system process; T-helper 1 cell differentiation; nervous system development; multicellular organism development; angiogenesis; regulation of endothelial cell migration; regulation of cell shape; negative regulation of angiogenesis; T cell differentiation involved in immune response; semaphorin-plexin signaling pathway; negative chemotaxis; neural crest cell migration; positive regulation of cell migration; negative regulation of axon extension involved in axon guidance; positive regulation of excitatory synapse assembly; positive regulation of inhibitory synapse assembly;
	Sources:Amigo / QuickGO
Orthologs
	64218
	20351
	ENSG00000196189
	ENSMUSG00000028064
	Q9H3S1
	Q62178
NM_001193300; NM_001193301; NM_001193302; NM_022367; NM_001370567;
	NM_001370568; NM_001370569; NM_001370571
	NM_001163489; NM_001163490; NM_001163491; NM_013658
NP_001180229; NP_001180230; NP_001180231; NP_071762; NP_001357496;
	NP_001357497; NP_001357498; NP_001357500
	NP_001156961; NP_001156962; NP_001156963; NP_038686
	Wikidata
View/Edit Human	View/Edit Mouse

Semaphorin-4A is a protein that in humans is encoded by the SEMA4A gene.