SEMA6C

SEMA6C
Identifiers
Aliases	SEMA6C, SEMAY, m-SemaY, m-SemaY2, semaphorin 6C, Sema-Y
External IDs	OMIM: 609294; MGI: 1338032; HomoloGene: 7931; GeneCards: SEMA6C; OMA:SEMA6C - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	151,146,631 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	95,174,024 bp
RNA expression pattern
	Top expressed in
	muscle of thigh; ; apex of heart; ; gastrocnemius muscle; ; right hemisphere of cerebellum; ; right testis; ; ganglionic eminence; ; left testis; ; Skeletal muscle tissue of rectus abdominis; ; triceps brachii muscle; ; left ventricle;
	Top expressed in
	muscle of thigh; ; triceps brachii muscle; ; temporal muscle; ; sternocleidomastoid muscle; ; spermatocyte; ; vastus lateralis muscle; ; intercostal muscle; ; pyloric antrum; ; tibialis anterior muscle; ; ankle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	semaphorin receptor binding; chemorepellent activity; neuropilin binding;
Cellular component	integral component of membrane; plasma membrane; membrane; integral component of plasma membrane; cytoplasm; cell surface; extracellular space;
Biological process	multicellular organism development; cell differentiation; nervous system development; axon guidance; negative regulation of axon extension; neural crest cell migration; positive regulation of cell migration; negative regulation of axon extension involved in axon guidance; negative chemotaxis; semaphorin-plexin signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	10500
	20360
	ENSG00000143434
	ENSMUSG00000038777
	Q9H3T2
	Q9WTM3
	NM_001178061; NM_001178062; NM_030913
	NM_001272024; NM_011351
	NP_001171532; NP_001171533; NP_112175
	NP_001258953; NP_035481
	Wikidata
View/Edit Human	View/Edit Mouse

Semaphorin-6C is a protein that in humans is encoded by the SEMA6C gene.

This gene product is a member of the semaphoring family of proteins. Semaphorins represent important molecular signals controlling multiple aspects of the cellular response that follows CNS injury, and thus may play an important role in neural regeneration.