SERINC3

SERINC3
Identifiers
Aliases	SERINC3, AIGP1, DIFF33, SBBI99, TDE, TDE1, TMS-1, serine incorporator 3
External IDs	OMIM: 607165; MGI: 1349457; HomoloGene: 38230; GeneCards: SERINC3; OMA:SERINC3 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	44,522,085 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	163,487,051 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; tendon of biceps brachii; ; Pons; ; internal globus pallidus; ; Brodmann area 23; ; middle temporal gyrus; ; superior frontal gyrus; ; stromal cell of endometrium; ; postcentral gyrus; ; prefrontal cortex;
	Top expressed in
	lobe of prostate; ; seminal vesicula; ; stroma of bone marrow; ; left lung lobe; ; blood; ; Paneth cell; ; median eminence; ; parotid gland; ; Gonadal ridge; ; crypt of lieberkuhn of small intestine;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	L-serine transmembrane transporter activity;
Cellular component	integral component of membrane; Golgi membrane; Golgi apparatus; membrane; cytoplasm; perinuclear region of cytoplasm; plasma membrane;
Biological process	phosphatidylserine metabolic process; detection of virus; innate immune response; defense response to virus; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; sphingolipid metabolic process; L-serine transport; immune system process; L-serine biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	10955
	26943
	ENSG00000132824
	ENSMUSG00000017707
	Q13530
	Q9QZI9
	NM_198941; NM_006811
	NM_012032
	NP_006802; NP_945179
	NP_036162
	Wikidata
View/Edit Human	View/Edit Mouse

Serine incorporator 3 is a protein that in humans is encoded by the SERINC3 gene. It has been demonstrated that SERINC3 acts as a retrovirus restriction factor.