SESN3

SESN3
Identifiers
Aliases	SESN3, SEST3, sestrin 3
External IDs	OMIM: 607768; MGI: 1922997; HomoloGene: 14386; GeneCards: SESN3; OMA:SESN3 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	95,232,541 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	14,244,397 bp
RNA expression pattern
	Top expressed in
	sperm; ; lateral nuclear group of thalamus; ; retinal pigment epithelium; ; internal globus pallidus; ; trigeminal ganglion; ; mucosa of paranasal sinus; ; epithelium of nasopharynx; ; Achilles tendon; ; spinal ganglia; ; external globus pallidus;
	Top expressed in
	ventromedial nucleus; ; lateral septal nucleus; ; molar; ; olfactory tubercle; ; saccule; ; mammillary body; ; ciliary body; ; nucleus accumbens; ; Amygdala; ; retinal pigment epithelium;
	More reference expression data
	n/a
Gene ontology
Molecular function	oxidoreductase activity; protein binding; oxidoreductase activity, acting on peroxide as acceptor; leucine binding;
Cellular component	nucleus; cytoplasm; GATOR2 complex; TORC2 complex;
Biological process	regulation of response to reactive oxygen species; negative regulation of TORC1 signaling; response to insulin; glucose homeostasis; regulation of protein kinase B signaling; TORC2 signaling; regulation of insulin receptor signaling pathway; cellular response to amino acid starvation; cellular response to glucose starvation; cellular response to amino acid stimulus; positive regulation of macroautophagy; cellular response to leucine; cellular response to leucine starvation;
	Sources:Amigo / QuickGO
Orthologs
	143686
	75747
	ENSG00000149212
	ENSMUSG00000032009
	P58005
	Q9CYP7
	NM_001271594; NM_144665
	NM_030261
	NP_001258523; NP_653266
	NP_084537
	Wikidata
View/Edit Human	View/Edit Mouse

Sestrin 3 is a protein that in humans is encoded by the SESN3 gene.