SETD7

SETD7
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1H3I, 1MT6, 1MUF, 1N6A, 1N6C, 1O9S, 1XQH, 2F69, 3CBM, 3CBO, 3CBP, 3M53, 3M54, 3M55, 3M56, 3M57, 3M58, 3M59, 3M5A, 3OS5, 3VUZ, 3VV0, 4E47, 4J7F, 4J8O, 4JDS, 4JLG, 5EG2, 5AYF
Identifiers
Aliases	SETD7, KMT7, SET7, SET7/9, SET9, SET domain containing lysine methyltransferase 7, SET domain containing 7, histone lysine methyltransferase
External IDs	OMIM: 606594; MGI: 1920501; HomoloGene: 12741; GeneCards: SETD7; OMA:SETD7 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	139,606,699 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	51,468,300 bp
RNA expression pattern
	Top expressed in
	tibialis anterior muscle; ; deltoid muscle; ; cardiac muscle tissue of right atrium; ; myocardium of left ventricle; ; skin of arm; ; quadriceps femoris muscle; ; Skeletal muscle tissue of rectus abdominis; ; biceps brachii; ; vastus lateralis muscle; ; Skeletal muscle tissue of biceps brachii;
	Top expressed in
	triceps brachii muscle; ; temporal muscle; ; sternocleidomastoid muscle; ; ciliary body; ; digastric muscle; ; lobe of cerebellum; ; cerebellar vermis; ; ankle; ; lateral geniculate nucleus; ; epithelium of lens;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	methyltransferase activity; transferase activity; p53 binding; chromatin binding; protein-lysine N-methyltransferase activity; protein binding; histone-lysine N-methyltransferase activity;
Cellular component	nucleoplasm; chromosome; nucleolus; nucleus;
Biological process	regulation of transcription, DNA-templated; peptidyl-lysine monomethylation; transcription, DNA-templated; cellular response to DNA damage stimulus; positive regulation of transcription, DNA-templated; peptidyl-lysine methylation; methylation; heterochromatin organization; peptidyl-lysine dimethylation; histone lysine methylation; response to ethanol; regulation of histone H3-K9 methylation; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	80854
	73251
	ENSG00000145391
	ENSMUSG00000037111
	Q8WTS6
	Q8VHL1
	NM_001306199; NM_001306200; NM_030648
	NM_080793
	NP_001293128; NP_001293129; NP_085151
	NP_542983
	Wikidata
View/Edit Human	View/Edit Mouse

Histone-lysine N-methyltransferase SETD7 is an enzyme that in humans is encoded by the SETD7 gene.