SET domain
| SET | |||||||||
|---|---|---|---|---|---|---|---|---|---|
structure and substrate of a histone H3 lysine methyltransferase from Paramecium bursaria chlorella virus 1 | |||||||||
| Identifiers | |||||||||
| Symbol | SET | ||||||||
| Pfam | PF00856 | ||||||||
| InterPro | IPR001214 | ||||||||
| SMART | SM0468 | ||||||||
| SCOP2 | 1ml9 / SCOPe / SUPFAM | ||||||||
| |||||||||
The SET domain is a protein domain that typically has methyltransferase activity. It was originally identified as part of a larger conserved region present in the Drosophila Trithorax protein and was subsequently identified in the Drosophila Su(var)3-9 and 'Enhancer of zeste' proteins, from which the acronym SET is derived [Su(var)3-9, Enhancer-of-zeste and Trithorax].