SF3B1

SF3B1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2F9D, 2F9J, 2PEH, 3LQV, 4OZ1, 2FHO
Identifiers
Aliases	SF3B1, Hsh155, MDS, PRP10, PRPF10, SAP155, SF3b155, splicing factor 3b subunit 1
External IDs	OMIM: 605590; MGI: 1932339; HomoloGene: 6696; GeneCards: SF3B1; OMA:SF3B1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	197,435,079 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	55,027,481 bp
RNA expression pattern
	Top expressed in
	tibia; ; ventricular zone; ; epithelium of nasopharynx; ; right uterine tube; ; skin of thigh; ; skin of hip; ; left ovary; ; superficial temporal artery; ; granulocyte; ; body of uterus;
	Top expressed in
	Gonadal ridge; ; hand; ; Rostral migratory stream; ; maxillary prominence; ; aortic valve; ; ascending aorta; ; human fetus; ; mandibular prominence; ; primitive streak; ; genital tubercle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; mRNA binding; RNA binding;
Cellular component	U11/U12 snRNP; catalytic step 2 spliceosome; spliceosomal complex; U12-type spliceosomal complex; U2-type prespliceosome; nucleus; U2 snRNP; nucleoplasm; nuclear speck; U2-type precatalytic spliceosome;
Biological process	RNA splicing, via transesterification reactions; epigenetic maintenance of chromatin in transcription-competent conformation; mRNA splicing, via spliceosome; spliceosomal complex assembly; mRNA processing; RNA splicing;
	Sources:Amigo / QuickGO
Orthologs
	23451
	81898
	ENSG00000115524
	ENSMUSG00000025982
	O75533
	Q99NB9
	NM_001005526; NM_001308824; NM_012433
	NM_031179
	NP_001005526; NP_001295753; NP_036565
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Splicing factor 3B subunit 1 is a protein that in humans is encoded by the SF3B1 gene.