SGCE

SGCE
Identifiers
Aliases	SGCE, DYT11, ESG, sarcoglycan epsilon, epsilon-SG
External IDs	OMIM: 604149; MGI: 1329042; HomoloGene: 31205; GeneCards: SGCE; OMA:SGCE - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	94,656,572 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	4,747,207 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; left ovary; ; right ovary; ; Achilles tendon; ; left adrenal gland; ; left adrenal cortex; ; tibial nerve; ; Descending thoracic aorta; ; right adrenal gland; ; ascending aorta;
	Top expressed in
	sciatic nerve; ; iris; ; white adipose tissue; ; umbilical cord; ; carotid body; ; adrenal gland; ; vestibular sensory epithelium; ; right lung lobe; ; efferent ductule; ; epididymis;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	cytoplasm; integral component of membrane; plasma membrane; Golgi apparatus; dendrite; sarcolemma; integral component of plasma membrane; dystrophin-associated glycoprotein complex; sarcoglycan complex; cell projection; cytoskeleton; dendrite membrane; membrane;
Biological process	muscle organ development; cell-matrix adhesion; muscle system process; membrane organization; skeletal muscle tissue development;
	Sources:Amigo / QuickGO
Orthologs
	8910
	20392
	ENSG00000127990
	ENSMUSG00000004631
	O43556
	O70258
NM_001099400; NM_001099401; NM_001301139; NM_003919; NM_001346713;
	NM_001346715; NM_001346717; NM_001346719; NM_001346720; NM_001362807; NM_001362808; NM_001362809
	NM_001130188; NM_001130189; NM_001130190; NM_001130191; NM_011360
NP_001092870; NP_001092871; NP_001288068; NP_001333642; NP_001333644;
	NP_001333646; NP_001333648; NP_001333649; NP_003910; NP_001349736; NP_001349737; NP_001349738
	NP_001123660; NP_001123661; NP_001123662; NP_001123663; NP_035490
	Wikidata
View/Edit Human	View/Edit Mouse

Epsilon-sarcoglycan is a protein that in humans is encoded by the SGCE gene.

The SGCE gene encodes the epsilon member of the sarcoglycan family, transmembrane components of the dystrophin-glycoprotein complex, which links the cytoskeleton to the extracellular matrix.[supplied by OMIM].