SGK2

SGK2
Identifiers
Aliases	SGK2, H-dJ138B7.2, serine/threonine kinase 2, serum/glucocorticoid regulated kinase 2
External IDs	OMIM: 607589; MGI: 1351318; HomoloGene: 8446; GeneCards: SGK2; OMA:SGK2 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	43,588,237 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	162,856,047 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; right lobe of liver; ; rectum; ; human kidney; ; C1 segment; ; renal medulla; ; duodenum; ; body of pancreas; ; kidney tubule; ; mucosa of ileum;
	Top expressed in
	right kidney; ; human kidney; ; left lobe of liver; ; proximal tubule; ; pyloric antrum; ; mucous cell of stomach; ; epithelium of stomach; ; large intestine; ; ileum; ; intestinal villus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ATP binding; calcium channel regulator activity; sodium channel regulator activity; protein kinase activity; potassium channel regulator activity; kinase activity; chloride channel regulator activity; nucleotide binding; transferase activity; protein serine/threonine kinase activity;
Cellular component	nucleus; intracellular anatomical structure; cytosol; cytoplasm; nucleoplasm; cellular component;
Biological process	response to oxidative stress; positive regulation of transporter activity; regulation of cell population proliferation; ion transmembrane transport; protein phosphorylation; intracellular signal transduction; peptidyl-serine phosphorylation; regulation of apoptotic process; phosphorylation; regulation of cell growth;
	Sources:Amigo / QuickGO
Orthologs
	10110
	27219
	ENSG00000101049
	ENSMUSG00000017868
	Q9HBY8; Q5H8Y5
	Q9QZS5
	NM_170693; NM_001199264; NM_016276
	NM_001291152; NM_001291154; NM_013731
	NP_001186193; NP_057360; NP_733794
	NP_001278081; NP_001278083; NP_038759
	Wikidata
View/Edit Human	View/Edit Mouse

Serine/threonine-protein kinase Sgk2 is an enzyme that in humans is encoded by the SGK2 gene.

This gene encodes a serine/threonine protein kinase. Although this gene product is similar to serum- and glucocorticoid-induced protein kinase (SGK), this gene is not induced by serum or glucocorticoids. This gene is induced in response to signals that activate phosphatidylinositol 3-kinase (PI3K), which is also true for SGK. Two alternate transcripts encoding two different isoforms have been described.