SGPP1

SGPP1
Identifiers
Aliases	SGPP1, SPPase1, sphingosine-1-phosphate phosphatase 1, SPP-1
External IDs	OMIM: 612826; MGI: 2135760; HomoloGene: 101696; GeneCards: SGPP1; OMA:SGPP1 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	63,728,065 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	75,782,503 bp
RNA expression pattern
	Top expressed in
	lymph node; ; placenta; ; islet of Langerhans; ; C1 segment; ; endometrium; ; human kidney; ; right lobe of liver; ; Brodmann area 9; ; Achilles tendon; ; prefrontal cortex;
	Top expressed in
	seminal vesicula; ; lobe of prostate; ; decidua; ; lacrimal gland; ; gastrula; ; skin of abdomen; ; proximal tubule; ; parotid gland; ; right kidney; ; gastric mucosa;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	hydrolase activity; sphingosine-1-phosphate phosphatase activity; dihydrosphingosine-1-phosphate phosphatase activity;
Cellular component	integral component of membrane; endoplasmic reticulum membrane; endoplasmic reticulum; membrane; plasma membrane; nucleus; nucleoplasm;
Biological process	intrinsic apoptotic signaling pathway; sphingosine metabolic process; sphingolipid biosynthetic process; extrinsic apoptotic signaling pathway; dephosphorylation; sphinganine-1-phosphate metabolic process; sphingolipid metabolic process; ER to Golgi ceramide transport; regulation of keratinocyte differentiation; regulation of epidermis development;
	Sources:Amigo / QuickGO
Orthologs
	81537
	81535
	ENSG00000126821; ENSG00000285281
	ENSMUSG00000021054
	Q9BX95
	Q9JI99
	NM_030791
	NM_030750
	NP_110418
	NP_109675
	Wikidata
View/Edit Human	View/Edit Mouse

Sphingosine-1-phosphate phosphatase 1 is an enzyme that in humans is encoded by the SGPP1 gene.