SH2B1

SH2B1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2HDV, 2HDX
Identifiers
Aliases	SH2B1, PSM, SH2B, SH2B adaptor protein 1
External IDs	OMIM: 608937; MGI: 1201407; HomoloGene: 32122; GeneCards: SH2B1; OMA:SH2B1 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	28,874,212 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	126,074,596 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; mucosa of transverse colon; ; right lobe of thyroid gland; ; right uterine tube; ; apex of heart; ; left lobe of thyroid gland; ; anterior pituitary; ; right ovary; ; left ovary; ; right frontal lobe;
	Top expressed in
	neural layer of retina; ; granulocyte; ; muscle of thigh; ; molar; ; lip; ; superior frontal gyrus; ; primary visual cortex; ; thymus; ; ankle; ; quadriceps femoris muscle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	signaling adaptor activity; protein binding; transmembrane receptor protein tyrosine kinase adaptor activity;
Cellular component	cytosol; nucleus; membrane; cytoplasm; plasma membrane;
Biological process	positive regulation of signal transduction; positive regulation of mitotic nuclear division; blood coagulation; lamellipodium assembly; signal transduction; regulation of DNA biosynthetic process; transmembrane receptor protein tyrosine kinase signaling pathway; intracellular signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	25970
	20399
	ENSG00000178188
	ENSMUSG00000030733
	Q9NRF2
	Q91ZM2
NM_001145795; NM_001145796; NM_001145797; NM_001145812; NM_001308293;
	NM_001308294; NM_015503; NM_001387404; NM_001387430
NM_001081459; NM_001289538; NM_001289539; NM_001289540; NM_001289541;
	NM_001289542; NM_011363
NP_001139267; NP_001139268; NP_001139269; NP_001139284; NP_001295222;
	NP_001295223; NP_056318
NP_001074928; NP_001276467; NP_001276468; NP_001276469; NP_001276470;
	NP_001276471; NP_035493
	Wikidata
View/Edit Human	View/Edit Mouse

SH2B adapter protein 1 is a protein that in humans is encoded by the SH2B1 gene.