SH3BP1

SH3BP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4J9D, 4J9F
Identifiers
Aliases	SH3BP1, ARHGAP43, SH3 domain binding protein 1
External IDs	OMIM: 617368; MGI: 104603; HomoloGene: 7534; GeneCards: SH3BP1; OMA:SH3BP1 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	37,656,117 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	78,796,251 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; monocyte; ; mucosa of transverse colon; ; skin of abdomen; ; spleen; ; skin of leg; ; rectum; ; lymph node; ; blood; ; appendix;
	Top expressed in
	granulocyte; ; lip; ; yolk sac; ; esophagus; ; mesenteric lymph nodes; ; thymus; ; superior frontal gyrus; ; genital tubercle; ; tail of embryo; ; primary visual cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	SH3 domain binding; protein binding; GTPase activator activity; semaphorin receptor binding;
Cellular component	cytoplasm; exocyst; lamellipodium; phagocytic cup; nucleus; cytosol; adherens junction; bicellular tight junction; cell junction; cell projection; cell leading edge; intracellular anatomical structure;
Biological process	signal transduction; phagocytosis, engulfment; actin filament organization; regulation of actin filament depolymerization; regulation of actin cytoskeleton organization; cell junction assembly; regulation of blood vessel endothelial cell migration; establishment of epithelial cell apical/basal polarity; negative regulation of small GTPase mediated signal transduction; semaphorin-plexin signaling pathway; phagocytosis; cell migration; positive regulation of GTPase activity; filopodium assembly; ruffle assembly;
	Sources:Amigo / QuickGO
Orthologs
	23616
	20401
	ENSG00000100092
	ENSMUSG00000022436
	Q9Y3L3
	P55194
	NM_018957; NM_001350055
	NM_009164; NM_001316684; NM_001316685; NM_001316686
	NP_061830; NP_001336984
	NP_001303613; NP_001303614; NP_001303615; NP_033190
	Wikidata
View/Edit Human	View/Edit Mouse

SH3 domain-binding protein 1 is a protein that in humans is encoded by the SH3BP1 gene.