SH3RF1

SH3RF1
Identifiers
Aliases	SH3RF1, POSH, RNF142, SH3MD2, SH3 domain containing ring finger 1
External IDs	MGI: 1913066; HomoloGene: 10988; GeneCards: SH3RF1; OMA:SH3RF1 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	169,270,956 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	61,849,105 bp
RNA expression pattern
	Top expressed in
	pancreatic epithelial cell; ; mucosa of ileum; ; palpebral conjunctiva; ; pancreatic ductal cell; ; endothelial cell; ; germinal epithelium; ; ventricular zone; ; mucosa of colon; ; jejunal mucosa; ; mucosa of paranasal sinus;
	Top expressed in
	efferent ductule; ; seminal vesicula; ; vestibular sensory epithelium; ; medial ganglionic eminence; ; primary oocyte; ; conjunctival fornix; ; vas deferens; ; secondary oocyte; ; retinal pigment epithelium; ; ciliary body;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; metal ion binding; transferase activity; MAP-kinase scaffold activity; ubiquitin protein ligase activity;
Cellular component	cytoplasm; perinuclear region of cytoplasm; cytosol; Golgi apparatus; cell projection; lamellipodium;
Biological process	negative regulation of extrinsic apoptotic signaling pathway; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of apoptotic process; regulation of JNK cascade; protein ubiquitination; apoptotic process; neuron migration; regulation of CD4-positive, alpha-beta T cell differentiation; protein autoubiquitination; regulation of CD8-positive, alpha-beta T cell proliferation; positive regulation of JNK cascade;
	Sources:Amigo / QuickGO
Orthologs
	57630
	59009
	ENSG00000154447
	ENSMUSG00000031642
	Q7Z6J0
	Q69ZI1
	NM_020870
	NM_021506; NM_198678
	NP_065921
	NP_067481
	Wikidata
View/Edit Human	View/Edit Mouse

Putative E3 ubiquitin-protein ligase SH3RF1 is an enzyme that in humans is encoded by the SH3RF1 gene.