Short-stature homeobox gene

SHOX
Identifiers
Aliases	SHOX, GCFX, PHOG, SHOXY, SS, short stature homeobox
External IDs	OMIM: 312865, 400020; HomoloGene: 55463; GeneCards: SHOX; OMA:SHOX - orthologs
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; protein binding; DNA-binding transcription activator activity, RNA polymerase II-specific; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; nucleoplasm; intracellular membrane-bounded organelle;
Biological process	multicellular organism development; skeletal system development; regulation of transcription, DNA-templated; transcription by RNA polymerase II; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	6473
	n/a
	ENSG00000185960
	n/a
	O15266
	n/a
	n/a
	n/a
	NP_000442; NP_006874
	n/a
	Wikidata
View/Edit Human

The short-stature homeobox gene (SHOX), also known as short-stature-homeobox-containing gene, is a gene located on both the X and Y chromosomes, which is associated with short stature in humans if mutated or present in only one copy (haploinsufficiency).