SIM1

SIM1
Identifiers
Aliases	SIM1, bHLHe14, single-minded family bHLH transcription factor 1, SIM bHLH transcription factor 1
External IDs	OMIM: 603128; MGI: 98306; HomoloGene: 3715; GeneCards: SIM1; OMA:SIM1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	100,464,921 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	50,865,248 bp
RNA expression pattern
	Top expressed in
	renal medulla; ; Skeletal muscle tissue of biceps brachii; ; human penis; ; Skeletal muscle tissue of rectus abdominis; ; corpus epididymis; ; caput epididymis; ; testicle; ; vastus lateralis muscle; ; islet of Langerhans; ; kidney tubule;
	Top expressed in
	supraoptic nucleus; ; inner renal medulla; ; paraventricular nucleus of hypothalamus; ; lumbar subsegment of spinal cord; ; mammillary body; ; right kidney; ; dorsomedial hypothalamic nucleus; ; soleus muscle; ; outer renal medulla; ; Bowman's capsule;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; protein dimerization activity; protein heterodimerization activity; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	regulation of transcription by RNA polymerase II; multicellular organism development; cell differentiation; ureteric bud development; regulation of transcription, DNA-templated; transcription, DNA-templated; nervous system development;
	Sources:Amigo / QuickGO
Orthologs
	6492
	20464
	ENSG00000112246
	ENSMUSG00000019913
	P81133
	Q61045
	NM_005068; NM_001374769
	NM_011376
	NP_005059; NP_001361698
	NP_035506
	Wikidata
View/Edit Human	View/Edit Mouse

Single-minded homolog 1, also known as class E basic helix-loop-helix protein 14 (bHLHe14), is a protein that in humans is encoded by the SIM1 gene.