SIN3A

SIN3A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1PO4
Identifiers
Aliases	SIN3A, Paired amphipathic helix protein Sin3a, SIN3 transcription regulator family member A, WITKOS
External IDs	OMIM: 607776; MGI: 107157; HomoloGene: 32124; GeneCards: SIN3A; OMA:SIN3A - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	75,455,842 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	57,035,650 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; ventricular zone; ; pancreatic ductal cell; ; bone marrow cells; ; testicle; ; ganglionic eminence; ; Achilles tendon; ; mucosa of ileum; ; tibial arteries; ; skin of limb;
	Top expressed in
	zygote; ; secondary oocyte; ; tail of embryo; ; primary oocyte; ; genital tubercle; ; ectoderm; ; otic placode; ; otic vesicle; ; saccule; ; epiblast;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; transcription corepressor activity; histone deacetylase activity; DNA-binding transcription factor activity; protein deacetylase activity; transcription factor binding; chromatin binding; transcription cis-regulatory region binding; protein binding; RNA binding; protein-containing complex binding;
Cellular component	transcription regulator complex; transcription repressor complex; nucleoplasm; nucleolus; chromatin; nucleus; kinetochore; Sin3 complex; protein-containing complex;
Biological process	negative regulation of protein localization to nucleus; regulation of transcription, DNA-templated; regulation of transcription from RNA polymerase II promoter in response to oxidative stress; rhythmic process; cellular response to dopamine; response to methylglyoxal; negative regulation of circadian rhythm; regulation of hormone levels; ageing; negative regulation of apoptotic process; in utero embryonic development; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; protein deacetylation; DNA replication; negative regulation of transcription regulatory region DNA binding; response to organonitrogen compound; hematopoietic progenitor cell differentiation; activation of innate immune response; positive regulation of G2/M transition of mitotic cell cycle; negative regulation of transcription, DNA-templated; histone deacetylation; negative regulation of histone H3-K27 acetylation; cellular response to glucose stimulus; positive regulation of transcription by RNA polymerase II; positive regulation of defense response to virus by host; regulation of lipid metabolic process; regulation of megakaryocyte differentiation; negative regulation of nucleic acid-templated transcription;
	Sources:Amigo / QuickGO
Orthologs
	25942
	20466
	ENSG00000169375
	ENSMUSG00000042557
	Q96ST3
	Q60520
	NM_001145357; NM_001145358; NM_015477
	NM_001110350; NM_001110351; NM_011378; NM_001357754
	NP_001138829; NP_001138830; NP_056292
	NP_001103820; NP_001103821; NP_035508; NP_001344683
	Wikidata
View/Edit Human	View/Edit Mouse

Paired amphipathic helix protein Sin3a is a protein that in humans is encoded by the SIN3A gene.