SIT1

SIT1
Identifiers
Aliases	SIT1, SIT, SIT-R, signaling threshold regulating transmembrane adaptor 1
External IDs	OMIM: 604964; MGI: 1889342; HomoloGene: 8694; GeneCards: SIT1; OMA:SIT1 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	35,650,931 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	43,483,734 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; lymph node; ; blood; ; spleen; ; thymus; ; appendix; ; superficial temporal artery; ; bone marrow cells; ; tonsil; ; mucosa of transverse colon;
	Top expressed in
	thymus; ; mesenteric lymph nodes; ; embryo; ; embryo; ; blood; ; spleen; ; subcutaneous adipose tissue; ; lumbar subsegment of spinal cord; ; granulocyte; ; epiblast;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; SH2 domain binding; kinase binding;
Cellular component	integral component of membrane; integral component of plasma membrane; plasma membrane; extracellular exosome; membrane;
Biological process	adaptive immune response; immune system process; T cell homeostasis; regulation of T cell activation; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	27240
	54390
	ENSG00000137078
	ENSMUSG00000028460
	Q9Y3P8
	Q8C503
	NM_014450
	NM_019436
	NP_055265
	NP_062309
	Wikidata
View/Edit Human	View/Edit Mouse

Signaling threshold-regulating transmembrane adapter 1 is a protein that in humans is encoded by the SIT1 gene.