Chloride potassium symporter 4

SLC12A4
Identifiers
Aliases	SLC12A4, KCC1, Chloride potassium symporter 4, CTC-479C5.17, hKCC1, solute carrier family 12 member 4
External IDs	OMIM: 604119; MGI: 1309465; HomoloGene: 21056; GeneCards: SLC12A4; OMA:SLC12A4 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	67,969,601 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	106,692,729 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; ascending aorta; ; stromal cell of endometrium; ; body of uterus; ; Descending thoracic aorta; ; right coronary artery; ; left lobe of thyroid gland; ; left coronary artery; ; tibial nerve; ; tibial arteries;
	Top expressed in
	choroid plexus of fourth ventricle; ; molar; ; Epithelium of choroid plexus; ; lip; ; ankle; ; stroma of bone marrow; ; body of femur; ; yolk sac; ; sciatic nerve; ; calvaria;
	More reference expression data
	n/a
Gene ontology
Molecular function	cation:chloride symporter activity; symporter activity; transporter activity; protein kinase binding; potassium:chloride symporter activity;
Cellular component	lysosomal membrane; plasma membrane; membrane; integral component of membrane; integral component of plasma membrane;
Biological process	ion transport; chemical synaptic transmission; cell volume homeostasis; potassium ion transport; potassium ion transmembrane transport; transmembrane transport; chloride transmembrane transport; chloride transport; transport; chloride ion homeostasis; potassium ion homeostasis; potassium ion import across plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	6560
	20498
	ENSG00000124067
	ENSMUSG00000017765
	Q9UP95
	Q9JIS8
	NM_005072; NM_001145961; NM_001145962; NM_001145963; NM_001145964
	NM_001253804; NM_009195
	NP_001139433; NP_001139434; NP_001139435; NP_001139436; NP_005063
	NP_001240733; NP_033221
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium-chloride transporter, member 4 is a chloride potassium symporter protein. It is encoded by the gene SLC12A4.