Peptide transporter 1

SLC15A1
Identifiers
Aliases	SLC15A1, HPECT1, HPEPT1, PEPT1, Peptide transporter 1, solute carrier family 15 member 1
External IDs	OMIM: 600544; MGI: 1861376; HomoloGene: 38006; GeneCards: SLC15A1; OMA:SLC15A1 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	98,752,672 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	121,742,664 bp
RNA expression pattern
	Top expressed in
	duodenum; ; jejunal mucosa; ; mucosa of ileum; ; gallbladder; ; vulva; ; skin of abdomen; ; skin of arm; ; skin of thigh; ; right lobe of liver; ; human penis;
	Top expressed in
	epithelium of small intestine; ; intestinal villus; ; jejunum; ; left colon; ; duodenum; ; ileum; ; esophagus; ; lip; ; skin of external ear; ; skin of back;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	proton-dependent oligopeptide secondary active transmembrane transporter activity; symporter activity; transporter activity; transmembrane transporter activity; oligopeptide transmembrane transporter activity; peptide:proton symporter activity; dipeptide transmembrane transporter activity; peptide transmembrane transporter activity;
Cellular component	integral component of membrane; plasma membrane; brush border; membrane; integral component of plasma membrane;
Biological process	protein transport; peptide transport; oligopeptide transport; oligopeptide transmembrane transport; ion transport; transmembrane transport; proton transmembrane transport; dipeptide transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	6564
	56643
	ENSG00000088386
	ENSMUSG00000025557
	P46059
	Q9JIP7
	NM_005073
	NM_053079
	NP_005064
	NP_444309
	Wikidata
View/Edit Human	View/Edit Mouse

Peptide transporter 1 (PepT 1) also known as solute carrier family 15 member 1 (SLC15A1) is a protein that in humans is encoded by SLC15A1 gene. PepT 1 is a solute carrier for oligopeptides. It functions in renal oligopeptide reabsorption and in the intestines in a proton dependent way, hence acting like a cotransporter.