SLC22A1

SLC22A1
Identifiers
Aliases	SLC22A1, HOCT1, OCT1, oct1_cds, solute carrier family 22 member 1
External IDs	OMIM: 602607; MGI: 108111; HomoloGene: 20665; GeneCards: SLC22A1; OMA:SLC22A1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	160,158,718 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	12,894,716 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; cartilage tissue; ; testicle; ; blood; ; granulocyte; ; spleen; ; stromal cell of endometrium; ; left lobe of thyroid gland; ; sural nerve; ; gastrocnemius muscle;
	Top expressed in
	right kidney; ; left lobe of liver; ; human kidney; ; proximal tubule; ; Ileal epithelium; ; duodenum; ; atrioventricular valve; ; jejunum; ; Paneth cell; ; gallbladder;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	norepinephrine:sodium symporter activity; protein homodimerization activity; transmembrane transporter activity; transporter activity; acetylcholine transmembrane transporter activity; monoamine transmembrane transporter activity; protein binding; identical protein binding; secondary active organic cation transmembrane transporter activity; quaternary ammonium group transmembrane transporter activity; organic cation transmembrane transporter activity; organic anion transmembrane transporter activity; dopamine:sodium symporter activity;
Cellular component	integral component of membrane; membrane; plasma membrane; integral component of plasma membrane; basolateral plasma membrane;
Biological process	establishment or maintenance of transmembrane electrochemical gradient; xenobiotic transmembrane transport; quaternary ammonium group transport; acetate ester transport; cation transport; ion transport; monoamine transport; norepinephrine transport; epinephrine transport; organic cation transport; dopamine transport; protein homooligomerization; ammonium transmembrane transport; transmembrane transport; neurotransmitter transport; organic anion transport; norepinephrine uptake; dopamine uptake;
	Sources:Amigo / QuickGO
Orthologs
	6580
	20517
	ENSG00000175003
	ENSMUSG00000023829
	O15245
	O08966
	NM_003057; NM_153187
	NM_009202
	NP_003048; NP_694857
	NP_033228
	Wikidata
View/Edit Human	View/Edit Mouse

Solute carrier family 22 member 1 is a protein that in humans is encoded by the gene SLC22A1.