Carnitine-acylcarnitine translocase

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Structures	Swiss-model
Domains	InterPro

solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
Identifiers
Symbol	SLC25A20
Alt. symbols	CACT
NCBI gene	788
HGNC	1421
OMIM	212138
RefSeq	NM_000387
UniProt	O43772
Other data
Locus	Chr. 3 p21.31
Structures
Search for
Structures	Swiss-model
Domains	InterPro

SLC25A20
Identifiers
Aliases	SLC25A20, CAC, CACT, Carnitine-acylcarnitine translocase, solute carrier family 25 member 20
External IDs	OMIM: 613698; MGI: 1928738; HomoloGene: 331; GeneCards: SLC25A20; OMA:SLC25A20 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	48,898,904 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	108,561,840 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; mucosa of transverse colon; ; apex of heart; ; mucosa of ileum; ; granulocyte; ; left ventricle; ; gastrocnemius muscle; ; duodenum; ; jejunal mucosa; ; muscle of thigh;
	Top expressed in
	brown adipose tissue; ; tunica adventitia of aorta; ; interventricular septum; ; intercostal muscle; ; soleus muscle; ; myocardium of ventricle; ; thoracic diaphragm; ; left lobe of liver; ; right ventricle; ; extraocular muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	acyl carnitine transmembrane transporter activity; carnitine:acyl carnitine antiporter activity; carnitine transmembrane transporter activity; transmembrane transporter activity;
Cellular component	membrane; mitochondrion; cytosol; mitochondrial inner membrane; integral component of membrane;
Biological process	carnitine shuttle; acyl carnitine transmembrane transport; mitochondrial transport; carnitine transport; carnitine transmembrane transport; transport;
	Sources:Amigo / QuickGO
Orthologs
	788
	57279
	ENSG00000178537
	ENSMUSG00000032602
	O43772
	Q9Z2Z6
	NM_000387
	NM_020520
	NP_000378
	NP_065266
	Wikidata
View/Edit Human	View/Edit Mouse

Carnitine-acylcarnitine translocase (CACT) is responsible for passive transport of carnitine and carnitine-fatty acid complexes and across the inner mitochondrial membrane as part of the carnitine shuttle system.