Chloride anion exchanger

SLC26A3
Identifiers
Aliases	SLC26A3, CLD, DRA, solute carrier family 26 member 3
External IDs	OMIM: 126650; MGI: 107181; HomoloGene: 55435; GeneCards: SLC26A3; OMA:SLC26A3 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	107,803,225 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	31,523,916 bp
RNA expression pattern
	Top expressed in
	mucosa of colon; ; mucosa of sigmoid colon; ; rectum; ; mucosa of transverse colon; ; seminal vesicula; ; mucosa of ileum; ; jejunal mucosa; ; duodenum; ; appendix; ; corpus epididymis;
	Top expressed in
	left colon; ; epithelium of small intestine; ; duodenum; ; seminal vesicula; ; ileum; ; jejunum; ; Paneth cell; ; efferent ductule; ; migratory enteric neural crest cell; ; cecum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	chloride transmembrane transporter activity; transporter activity; DNA-binding transcription factor activity; transcription coregulator activity; sulfate transmembrane transporter activity; secondary active sulfate transmembrane transporter activity; bicarbonate transmembrane transporter activity; oxalate transmembrane transporter activity; protein binding; antiporter activity; chloride channel activity; inorganic anion exchanger activity;
Cellular component	integral component of membrane; membrane; plasma membrane; integral component of plasma membrane; brush border membrane; apical plasma membrane; sperm midpiece;
Biological process	excretion; intracellular pH elevation; membrane hyperpolarization; sulfate transport; regulation of membrane potential; regulation of intracellular pH; ion transport; anion transport; bicarbonate transport; sperm capacitation; chloride transport; cellular response to cAMP; regulation of transcription, DNA-templated; chloride transmembrane transport; oxalate transport; sulfate transmembrane transport; transmembrane transport; regulation of nucleic acid-templated transcription; anion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	1811
	13487
	ENSG00000091138
	ENSMUSG00000001225
	P40879
	Q9WVC8
	NM_000111
	NM_021353
	NP_000102
	NP_067328
	Wikidata
View/Edit Human	View/Edit Mouse

Chloride anion exchanger, also known as down-regulated in adenoma (protein DRA), is a protein that in humans is encoded by the SLC26A3 gene.