Plasma membrane monoamine transporter

SLC29A4
Identifiers
Aliases	SLC29A4, ENT4, PMAT, solute carrier family 29 member 4, Plasma membrane monoamine transporter
External IDs	OMIM: 609149; MGI: 2385330; HomoloGene: 71345; GeneCards: SLC29A4; OMA:SLC29A4 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	5,306,912 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	142,708,245 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; islet of Langerhans; ; Hypothalamus; ; internal globus pallidus; ; ganglionic eminence; ; anterior cingulate cortex; ; right frontal lobe; ; external globus pallidus; ; substantia nigra; ; lateral nuclear group of thalamus;
	Top expressed in
	Epithelium of choroid plexus; ; dentate gyrus of hippocampal formation granule cell; ; neural tube; ; facial motor nucleus; ; cerebellar cortex; ; ganglionic eminence; ; ventricular zone; ; external carotid artery; ; primary visual cortex; ; internal carotid artery;
	More reference expression data
	n/a
Gene ontology
Molecular function	monoamine transmembrane transporter activity; nucleoside transmembrane transporter activity;
Cellular component	integral component of membrane; plasma membrane; apical plasma membrane; membrane;
Biological process	nucleoside transmembrane transport; monoamine transport; transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	222962
	243328
	ENSG00000164638
	ENSMUSG00000050822
	Q7RTT9
	Q8R139
	NM_001040661; NM_001300847; NM_153247
	NM_146257
	NP_001035751; NP_001287776; NP_694979
	NP_666369
	Wikidata
View/Edit Human	View/Edit Mouse

The plasma membrane monoamine transporter (PMAT) is a low-affinity monoamine transporter protein which in humans is encoded by the SLC29A4 gene. It is known alternatively as the human equilibrative nucleoside transporter-4 (hENT4). It was discovered in 2004 and has been identified as a potential alternate target for treating various conditions.