Proton-coupled amino acid transporter 1

SLC36A1
Identifiers
Aliases	SLC36A1, Dct1, LYAAT1, PAT1, TRAMD3, solute carrier family 36 member 1
External IDs	OMIM: 606561; MGI: 2445299; HomoloGene: 121860; GeneCards: SLC36A1; OMA:SLC36A1 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	151,492,379 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	55,127,156 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; duodenum; ; right hemisphere of cerebellum; ; mucosa of ileum; ; trabecular bone; ; trigeminal ganglion; ; mucosa of colon; ; rectum; ; tendon of biceps brachii; ; mucosa of sigmoid colon;
	Top expressed in
	superior cervical ganglion; ; spinal ganglia; ; lumbar spinal ganglion; ; visual cortex; ; left colon; ; jejunum; ; stroma of bone marrow; ; yolk sac; ; primary visual cortex; ; islet of Langerhans;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	amino acid:proton symporter activity; L-proline transmembrane transporter activity; neutral amino acid transmembrane transporter activity; proton transmembrane transporter activity; L-alanine transmembrane transporter activity; glycine transmembrane transporter activity; symporter activity; amino acid transmembrane transporter activity;
Cellular component	integral component of membrane; membrane; plasma membrane; lysosomal membrane; endoplasmic reticulum; lysosome;
Biological process	L-alanine transport; proton transmembrane transport; proline transmembrane transport; ion transport; proline transport; amino acid transport; glycine transport; neutral amino acid transport; transmembrane transport; amino acid transmembrane transport; transport;
	Sources:Amigo / QuickGO
Orthologs
	206358
	215335
	ENSG00000123643
	ENSMUSG00000020261
	Q7Z2H8
	Q8K4D3
	NM_001308150; NM_001308151; NM_078483; NM_001349740
	NM_153139
	NP_001295079; NP_001295080; NP_510968; NP_001336669
	NP_694779
	Wikidata
View/Edit Human	View/Edit Mouse

Proton-coupled amino acid transporter 1 is a protein that in humans is encoded by the SLC36A1 gene.

This gene encodes a member of the eukaryote-specific amino acid/auxin permease (AAAP) 1 transporter family. The encoded protein functions as a proton-dependent, small amino acid transporter. This gene is clustered with related family members on chromosome 5q33.1.