Zinc transporter ZIP1

SLC39A1
Identifiers
Aliases	SLC39A1, ZIP1, ZIRTL, solute carrier family 39 member 1
External IDs	OMIM: 604740; MGI: 1353474; HomoloGene: 40906; GeneCards: SLC39A1; OMA:SLC39A1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	153,968,184 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	90,160,919 bp
RNA expression pattern
	Top expressed in
	placenta; ; Achilles tendon; ; upper lobe of left lung; ; right lung; ; stromal cell of endometrium; ; gallbladder; ; right adrenal gland; ; left adrenal gland; ; Descending thoracic aorta; ; ascending aorta;
	Top expressed in
	prostate; ; umbilical cord; ; epidermis; ; lip; ; uterus; ; placenta; ; urinary bladder; ; gallbladder; ; duodenum; ; stomach;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metal ion transmembrane transporter activity; inorganic cation transmembrane transporter activity; zinc ion transmembrane transporter activity; signaling receptor binding;
Cellular component	integral component of membrane; plasma membrane; endoplasmic reticulum membrane; membrane; endoplasmic reticulum;
Biological process	embryonic cranial skeleton morphogenesis; metal ion transport; zinc ion transmembrane transport; cation transport; zinc ion transport; in utero embryonic development; ion transport; limb development; transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	27173
	30791
	ENSG00000143570
	ENSMUSG00000052310
	Q9NY26
	Q9QZ03
NM_014437; NM_001271957; NM_001271958; NM_001271959; NM_001271960;
	NM_001271961
	NM_013901
NP_001258886; NP_001258887; NP_001258888; NP_001258889; NP_001258890;
	NP_055252
	NP_038929
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc transporter ZIP1 is a protein that in humans is encoded by the SLC39A1 gene.

The protein ZIP1 is responsible for the active transport of zinc into prostate cells. In many prostate cancers SLC39A1 is silenced causing prostate cancer cells to be low in zinc.