Zinc transporter SLC39A7

SLC39A7
Identifiers
Aliases	SLC39A7, D6S115E, D6S2244E, H2-KE4, HKE4, KE4, RING5, ZIP7, solute carrier family 39 member 7, AGM9
External IDs	OMIM: 601416; MGI: 95909; HomoloGene: 5072; GeneCards: SLC39A7; OMA:SLC39A7 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	33,204,439 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	34,250,656 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; islet of Langerhans; ; body of pancreas; ; placenta; ; mucosa of transverse colon; ; pituitary gland; ; anterior pituitary; ; rectum; ; smooth muscle tissue; ; left adrenal gland;
	Top expressed in
	islet of Langerhans; ; adrenal gland; ; placenta; ; lens; ; yolk sac; ; Mesencephalon; ; white adipose tissue; ; stomach; ; urinary bladder; ; lung;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metal ion transmembrane transporter activity; protein binding; zinc ion transmembrane transporter activity;
Cellular component	integral component of membrane; Golgi apparatus; endoplasmic reticulum membrane; endoplasmic reticulum; membrane; nucleoplasm;
Biological process	metal ion transport; zinc ion transmembrane transport; zinc ion transport; ion transport; cellular zinc ion homeostasis; transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	7922
	14977
ENSG00000227402; ENSG00000229802; ENSG00000226614; ENSG00000112473; ENSG00000206288;
	ENSG00000224399
	ENSMUSG00000024327
	Q92504
	Q31125
	NM_006979; NM_001077516; NM_001288777
	NM_001077709; NM_008202
	NP_001070984; NP_001275706; NP_008910; NP_001070984.1; NP_008910.2
	NP_001071177; NP_032228
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc transporter SLC39A7 (ZIP7), also known as solute carrier family 39 member 7, is a transmembrane protein that in humans is encoded by the SLC39A7 gene. It belongs to the ZIP family, which consists of 14 proteins that transport zinc into the cytoplasm. Its primary role is to control the transport of zinc from the ER and Golgi apparatus to the cytoplasm. It also plays a role in glucose metabolism. Its structure consists of helices that bind to zinc in a binuclear metal center. Its fruit fly orthologue is Catsup.