SLC41A1

SLC41A1
Identifiers
Aliases	SLC41A1, MgtE, solute carrier family 41 member 1, NPHPL2
External IDs	OMIM: 610801; MGI: 2444823; HomoloGene: 14871; GeneCards: SLC41A1; OMA:SLC41A1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	205,813,748 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	131,776,603 bp
RNA expression pattern
	Top expressed in
	myocardium of left ventricle; ; cardiac muscle tissue of right atrium; ; apex of heart; ; right ventricle; ; right auricle of heart; ; tibialis anterior muscle; ; body of tongue; ; body of pancreas; ; vena cava; ; Skeletal muscle tissue of biceps brachii;
	Top expressed in
	extraocular muscle; ; digastric muscle; ; saccule; ; stria vascularis; ; optic nerve; ; soleus muscle; ; thoracic diaphragm; ; sternocleidomastoid muscle; ; ciliary body; ; plantaris muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	cation transmembrane transporter activity; magnesium ion transmembrane transporter activity; magnesium:sodium antiporter activity; transmembrane transporter activity;
Cellular component	integral component of membrane; membrane; plasma membrane; basolateral plasma membrane; protein-containing complex;
Biological process	cation transport; ion transport; sodium ion transmembrane transport; magnesium ion transmembrane transport; cellular magnesium ion homeostasis; magnesium ion transport; cellular response to magnesium ion;
	Sources:Amigo / QuickGO
Orthologs
	254428
	98396
	ENSG00000133065
	ENSMUSG00000013275
	Q8IVJ1
	Q8BJA2
	NM_173854
	NM_173865
	NP_776253
	NP_776290
	Wikidata
View/Edit Human	View/Edit Mouse

SLC41A1 is a protein that in humans is encoded by the gene SLC41A1. It is homologous to the prokaryotic Mg++ transfer protein MgtE

Mutations in this gene have been associated to Nephronophthisis-like phenotypes.