SLC45A3

SLC45A3
Identifiers
Aliases	SLC45A3, IPCA-2, IPCA-6, IPCA-8, IPCA6, PCANAP2, PCANAP6, PCANAP8, PRST, solute carrier family 45 member 3
External IDs	OMIM: 605097; MGI: 1922082; HomoloGene: 23813; GeneCards: SLC45A3; OMA:SLC45A3 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	205,680,509 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	131,910,707 bp
RNA expression pattern
	Top expressed in
	prostate; ; C1 segment; ; oocyte; ; nasal epithelium; ; secondary oocyte; ; mucosa of ileum; ; right lobe of liver; ; spleen; ; inferior ganglion of vagus nerve; ; mucosa of transverse colon;
	Top expressed in
	secondary oocyte; ; primary oocyte; ; zygote; ; gastric mucosa; ; pyloric antrum; ; mucous cell of stomach; ; epithelium of stomach; ; egg cell; ; lumbar spinal ganglion; ; right kidney;
	More reference expression data
	n/a
Gene ontology
Molecular function	sucrose:proton symporter activity; sugar transmembrane transporter activity;
Cellular component	integral component of membrane; membrane; plasma membrane;
Biological process	transmembrane transport; sucrose transport; positive regulation of glucose metabolic process; positive regulation of fatty acid biosynthetic process; regulation of oligodendrocyte differentiation; hexose transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	85414
	212980
	ENSG00000158715
	ENSMUSG00000026435
	Q96JT2
	Q8K0H7
	NM_033102
	NM_001177628; NM_145977
	NP_149093
	NP_001171099; NP_666089
	Wikidata
View/Edit Human	View/Edit Mouse

Solute carrier family 45 member 3 (SLC45A3), also known as prostate cancer-associated protein 6 or prostein, is a protein that in humans is encoded by the SLC45A3 gene.

SLC45A3 is expressed in a prostate-specific manner by normal tissues and at a significantly lower level in prostate tumor cell lines. Treatment of prostate cancer cell lines with androgens upregulates the expression of SLC45A3.