Multidrug and toxin extrusion protein 1

SLC47A1
Identifiers
Aliases	SLC47A1, MATE1, solute carrier family 47 member 1
External IDs	OMIM: 609832; MGI: 1914723; HomoloGene: 34364; GeneCards: SLC47A1; OMA:SLC47A1 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	19,579,034 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	61,269,171 bp
RNA expression pattern
	Top expressed in
	right adrenal cortex; ; kidney tubule; ; left adrenal cortex; ; glomerulus; ; metanephric glomerulus; ; right lobe of liver; ; human kidney; ; canal of the cervix; ; gastrocnemius muscle; ; gonad;
	Top expressed in
	proximal tubule; ; right kidney; ; human kidney; ; left lobe of liver; ; lumbar spinal ganglion; ; interventricular septum; ; myocardium of ventricle; ; cardiac muscles; ; extraocular muscle; ; digastric muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	antiporter activity; monovalent cation:proton antiporter activity; xenobiotic transmembrane transporter activity;
Cellular component	integral component of membrane; plasma membrane; membrane; vesicle;
Biological process	proton transmembrane transport; transmembrane transport; xenobiotic export; xenobiotic transmembrane transport; organic cation transport; cation transport; xenobiotic transport;
	Sources:Amigo / QuickGO
Orthologs
	55244
	67473
	ENSG00000142494
	ENSMUSG00000010122
	Q96FL8
	Q8K0H1
	NM_018242
	NM_026183
	NP_060712
	NP_080459
	Wikidata
View/Edit Human	View/Edit Mouse

Multidrug and toxin extrusion protein 1 (MATE1), also known as solute carrier family 47 member 1, is a protein that in humans is encoded by the SLC47A1 gene. SLC47A1 belongs to the MATE (multidrug and toxic compound extrusion) family of transporters that are found in bacteria, archaea and eukaryotes.