Electroneutral sodium bicarbonate exchanger 1

SLC4A8
Identifiers
Aliases	SLC4A8, NBC3, NDCBE, solute carrier family 4 member 8
External IDs	OMIM: 605024; MGI: 1928745; HomoloGene: 68419; GeneCards: SLC4A8; OMA:SLC4A8 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	51,515,763 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	100,721,849 bp
RNA expression pattern
	Top expressed in
	Pons; ; Brodmann area 23; ; superior vestibular nucleus; ; corpus callosum; ; middle temporal gyrus; ; ventral tegmental area; ; postcentral gyrus; ; inferior ganglion of vagus nerve; ; lateral nuclear group of thalamus; ; cerebellar vermis;
	Top expressed in
	spermatocyte; ; spermatid; ; zygote; ; neural layer of retina; ; secondary oocyte; ; lumbar subsegment of spinal cord; ; superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; primary oocyte; ; cerebellar cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	antiporter activity; inorganic anion exchanger activity; anion transmembrane transporter activity; sodium:bicarbonate symporter activity;
Cellular component	integral component of membrane; neuronal cell body membrane; neuron projection; plasma membrane; membrane; integral component of plasma membrane;
Biological process	anion transport; sodium ion transport; regulation of intracellular pH; inorganic anion transport; ion transport; bicarbonate transport; transmembrane transport; anion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	9498
	59033
	ENSG00000050438
	ENSMUSG00000023032
	Q2Y0W8
	Q8JZR6
NM_001039960; NM_001258401; NM_001258402; NM_001258403; NM_001267615;
	NM_004858; NM_001405266; NM_001405268; NM_001405270
	NM_001033218; NM_021530; NM_001347102
	NP_001035049; NP_001245330; NP_001245331; NP_001245332; NP_001254544
	NP_001334031; NP_067505
	Wikidata
View/Edit Human	View/Edit Mouse

Electroneutral sodium bicarbonate exchanger 1 is a protein that in humans is encoded by the SLC4A8 gene.